Surgeons at Addenbrooke's Major Trauma Centre must operate on a single mum who has a severed spinal cord and a critically injured motorcyclist. Surgeons at Addenbrooke's Hospital perform brain surgery on a patient who is awake and attempt to repair a section of the body's biggest blood vessel that's threatening to burst. Surgeons at Addenbrooke's operate against the clock to remove a kidney from a husband and transplant it into his wife, who is in end-stage kidney failure. Addenbrooke's surgeons take on two high-risk operations; surgery to excise tumours near the spinal cord and a procedure to remove a dangerous mass off the body's largest vein. Addenbrooke's surgeons perform life changing scoliosis surgery to straighten the spine of their 17-year-old patient but face the risk of causing paralysis. Surgeons at Addenbrooke's Major Trauma Centre must operate on two road accident victims who have suffered life-changing injuries so serious they could lead to an amputation.